This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: -/- The main aim of this review will be to assess the effects of changing practitioner empathy or patient expectations for all conditions. The main objective is to conduct a systematic review of randomised trials where the intervention involves manipulating either (a) practitioner empathy or (b) patient expectations, or (c) both.

In this paper, we provide an account of the ontological status of Christ’s dead body, which remained in the tomb during the three days after his crucifixion. Our account holds that Christ’s dead body – during the time between his death and resurrection – was prime matter without a substantial form. We defend this account by showing how it is metaphysically possible for prime matter to exist in actuality without substantial forms. Our argument turns on the truth of two theses: (...) God is able to produce all acts of secondary causes without those secondary causes, and Substantial forms are secondary causes of the actuality of prime matter. We argue that the metaphysical possibility of matter without form is perfectly consistent with holding both there is only one substantial form in a material substance and that prime matter is pure potentiality. Moreover, we argue that the metaphysical possibility of matter without form does little-to-no damage to our natural understanding of material substances. (shrink)

The development of possible worlds semantics for modal claims has led to a more general application of that theory as a complete semantics for various formal and natural languages, and this view is widely held to be an adequate (philosophical) interpretation of the model theory for such languages. We argue here that this view generates a self-referential inconsistency that indicates either the falsity or the incompleteness of PWS.

In this paper it is argued that the conjunction of linguistic ersatzism, the ontologically deflationary view that possible worlds are maximal and consistent sets of sentences, and possible world semantics, the view that the meaning of a sentence is the set of possible worlds at which it is true, implies that no actual speaker can effectively use virtually any language to successfully communicate information. This result is based on complexity issues that relate to our finite computational ability to deal with (...) large bodies of information and a strong, but well motivated, assumption about the cognitive accessibility of meanings of sentences ersatzers seem to be implicitly committed to. It follows that linguistic ersatzism, possible world semantics, or both must be rejected. (shrink)

Mimesis can refer to imitation, emulation, representation, or reenactment - and it is a concept that links together many aspects of ancient Greek Culture. The Western Greek bell-krater on the cover, for example, is painted with a scene from a phlyax play with performers imitating mythical characters drawn from poetry, which also represent collective cultural beliefs and practices. One figure is shown playing a flute, the music from which might imitate nature, or represent deeper truths of the cosmos based upon (...) Pythagorean views (which were widespread in Western Greece at the time). The idea that mimesis should be restricted to ideals was made famous by Plato (whose connections to Pythagoreanism and Siracusa are well-known), and famously challenged by his student Aristotle (not to mention by the mimetic character of Plato’s own poetry). This volume gathers essays not only on the philosophical debate about mimesis, but also on its use in architecture, drama, poetry, history, music, ritual, and visual art. The emphasis is on examples from Hellenic cities in Southern Italy and Sicily, but the insights apply far beyond – even to modern times. Contributors include: Thomas Noble Howe, Francisco J. Gonzalez, Gene Fendt, Guilherme Domingues da Motta, Jeremy DeLong, Carolina Araújo, Marie-Élise Zovko, Lidia Palumbo, Sean Driscoll, Konstantinos Gkaleas, Anna Motta, Jure Zovko, Alexander H. Zistakis, Christos C. Evangeliou, Dorota Tymura, Iris Sulimani, Elliott Domagola, Jonah Radding, Giulia Corrente, Laura Tisi, Ewa Osek, Argyri G. Karanasiou, Rocío Manuela Cuadra Rubio, Jorge Tomás García, Aura Piccioni, and José Miguel Puebla Morón. (shrink)

Le présent travail s'inscrit à l'intersection de deux problèmes épistémologiques majeurs. D'une part, le problème de la démarcation scientifique, qui consiste à identifier ce qui distingue intrinsèquement un système (un énoncé, une théorie, ...) scientifique d'un système non scientifique ou pseudo-scientifique. D'autre part, le problème de l'unité épistémologique des sciences, qui consiste à se demander si toutes les disciplines à vocation scientifique peuvent être vues comme des instanciations d'une notion unique de la scientificité. Ces deux problèmes ont soulevé de nombreux (...) débats ayant mis en évidence un ensemble important de difficultés. Le terme « scientifique » désigne en effet des méthodes empiriques, des constructions théoriques et des pratiques de recherche si hétérogènes qu’il semble voué à l’échec d’en chercher une définition aisée à circonscrire. De plus, les objets des disciplines scientifiques sont eux-mêmes de natures très diverses, ce qui semble rendre pareillement caduque toute recherche d’un concept unique de science qui pourrait s’appliquer indépendamment de la discipline en question. Dans cette thèse, je me propose de prendre à contre-pied cet état de fait en soutenant la possibilité et la pertinence d'un modèle unitaire de la scientificité, tout en me restreignant à une approche épistémologique comparée entre les sciences physiques et les sciences sociales. Pour défendre mon propos, j’ai mobilisé deux types de réponses pouvant être opposées au constat présenté plus haut. D’une part, des réponses de principe, où j’examine et m’oppose à des arguments théoriques soutenant l’impossibilité ou en tout cas la difficulté de définir la scientificité en général, et la nécessité pour les sciences sociales de jouir d’une définition à part. D’autre part, je mobilise également des réponses par l’exemple. J’étudie alors plus en détail l’approche dite « analytique » en sociologie. Ce courant a cela d’intéressant pour mon propos qu’il ne semble pas nécessiter d’épistémologie alternative à celle ayant cours, par exemple, en physique ou en biologie, tout en prétendant bien produire des connaissances sur le monde social. Il s’agit donc d’un contre-exemple concret et manifeste de la thèse soutenant que la sociologie ne peut pas jouir du même type d’épistémologie que les autres disciplines. Plus concrètement, j’élabore un (méta-)modèle unitaire de la scientificité en me concentrant sur une unité d’analyse bien circonscrite : les modèles. Je distingue chez ses derniers, classiquement, deux composantes principales : une composante empirique, qui a pour vocation à identifier des régularités dans le réel auquel on a accès à travers des données, et une composante théorique, à visée explicative et classificatoire. Je propose alors de construire formellement un degré de scientificité global dans lequel se combinent la maximisation d’une certaine quantité d’information définie sur la composante empirique et un critère d’invariance structurelle défini sur la composante théorique. Ces diverses constructions, bien que formelles, permettent d’éclairer efficacement les questions épistémologiques que je me suis données au départ de mon travail, ce dernier ayant vocation à constituer une étape supplémentaire vers un modèle unitaire de la scientificité. (shrink)

In this chapter, I will explore the intersection of philosophy and childhood through the intriguing case study of J. S. Mill, who was almost completely denied a childhood—in the nineteenth-century sense of a qualitatively distinct period inclusive of greater play, imaginative freedom, flexibility, and education. For his part, Mill’s lack of such a childhood was the direct result of his father, James Mill (economic theorist and early proponent of Utilitarianism), who in a letter to Jeremy Bentham explicitly formulates a (...) plan to raise his son as an experiment in the Utilitarian “science” of ethics. More specifically, although James Mill’s end was to create a near-superhuman champion of Utilitarianism, his means to that end included denying John access to other children and the Romantic poetry of his contemporaries. Despite this oppressive lack of a childhood, however, J. S. Mill went on to become perhaps the most influential social and political reformer in British history, especially in regard to gender relations through his groundbreaking work for women’s suffrage. This begs the central question of this chapter, namely how could a philosopher’s tyrannized childhood nevertheless lead to his later overturning of such tyranny in the political sphere? (shrink)

OBJETIVO -/- O estudante de Zootecnia e de Veterinária, quando se depara com a produção animal, um dos pilares importantes é a reprodução, uma vez que é a perpetuação da espécie, seja para gerar filhas de uma vaca campeã em produção leiteira e de um touro com rusticidade e com aptidão produtiva de corte, ou mesmo para reposição de um plantel, o mesmo deve estar consciente de que esse ramo é de extrema responsabilidade, já que estará intimamente lidando com a (...) vida e com um investimento que pode gerar lucros em demasia para a propriedade ou, se mal feito o manejo da reprodução, trazer sérios transtornos para a mesma. -/- Nesse trabalho, o estudante revisará os sucessos da puberdade e estacionalidade reprodutiva relacionando-os com os processos endócrinos e os fatores que afetam sua manifestação como os nutricionais, para compreender a maneira ao qual podem ser manipuladas. -/- -/- • _____INTRODUÇÃO -/- A puberdade marca o início da vida reprodutiva do animal, permitindo integrar o indivíduo ao seu ciclo produtivo. A estacionalidade é uma característica de adaptação que algumas espécies desenvolveram para fazer garantir a eficiência da reprodução e a sobrevivência dos filhotes. -/- -/- • _____PUBERDADE -/- A puberdade é atingida quando o animal é capaz de produzir e liberar gametas viáveis e funcionais (férteis). Na fêmea esse fato ocorre na primeira ovulação, que geralmente coincide com a manifestação do comportamento do cio; e nos machos durante a primeira ejaculação com espermatozoides viáveis. -/- Do ponto de vista da produção animal, puberdade prematura ou precoce, é importante para poder permitir a incorporação dos animais ao ciclo produtivo o mais rapidamente possível. No caso de touros holandeses, por exemplo, é desejável que produzam sêmen precocemente para incorporá-los a prova de progênie; nas fêmeas, entretanto, deve-se considerar que nem sempre é conveniente usar o primeiro ciclo ou cio para reprodução. É o caso das marrãs (porcas primíparas), onde é benéfico esperar até o segundo ou terceiro estro para aumentar o tamanho da ninhada. Também pode ser vantajoso esperar que o indivíduo alcance sua maturidade sexual, que ocorre quando a fêmea consegue se reproduzir sem sofrer efeitos adversos. A ovelha nascida na primavera, por exemplo, pode engravidar no outono seguinte e dar à luz no primeiro ano de vida, mas seu crescimento pode ser afetado; o mesmo ocorre com a novilha, em que o acasalamento precoce pode promover distorcia por falta de desenvolvimento pélvico. -/- A puberdade é um processo gradual e está intimamente relacionada à taxa de crescimento e ao metabolismo energético. O recém-nascido usa energia para funções vitais, principalmente termorregulação; esse feito se deve ao fato de os jovens possuírem uma superfície corporal muito elevada em relação ao seu volume. Durante o desenvolvi-mento subsequente dos tecidos também há prioridade no uso de nutrientes, que inicialmente favorecem o desenvolvimento do tecido ósseo e muscular, e uma vez que estes atingem determinado tamanho de acordo com as condições genéticas do indivíduo, inicia-se o desenvolvimento do tecido adiposo, que é indicativa de um reservatório de energia. É importante ressaltar que existe uma interação entre a genética e o meio ambiente, de forma que o potencial genético só será expresso se o meio ambiente for favorável. -/- Para que a ovulação ocorra, é necessário considerar o funcionamento do eixo hipotálamo-hipófise-gonodal. O aumento da frequência pulsátil do GnRH hipotalâmico e em consequência do LH hipofisário provoca a maturação do folículo em nível gonodal, o que aumenta a produção de estrógenos. O aumento dos estrogênios causa, por feedback positivo no hipotálamo, a liberação do pico pré-ovulatório de LH e, consequentemente, a ovulação. Na fase pré-púbere, a frequência dos pulsos de GnRH e LH é muito baixa e insuficiente para provocar a maturação folicular, pois o hipotálamo é inibido e, portanto, não ocorre ovulação. -/- A geração pulsátil de GnRH no momento reprodutivo adequado para desencadear o início da puberdade depende de uma rede neural complexa que, além dos neurônios GnRH, inclui outros neurônios e células da glia; ele também integra vários sinais internos e externos para o corpo. A morfologia dos neurônios GnRH também é única, uma vez que seus dendritos também podem funcionar como axônios, dando-lhes uma função distinta. A geração de pulsos também indica a necessidade de sincronização entre subpopulações de neurônios GnRH, que, acima de tudo, parece ser extrínseca a esses neurônios e envolve múltiplos hormônios e neurotransmissores -/- Se dois níveis de conexões aferentes são considerados, estima-se que cada neurônio de GnRH pode ser conectado a cerca de cinco milhões de outros neurônios; milhares de genes, então, podem estar envolvidos no processo da puberdade. A importância funcional e hierárquica de cada um desses genes no controle dos neurônios GnRH, juntamente com outros fatores neuronais e gliais, pode diferir entre as espécies. Existem, no entanto, componentes fundamentais que parecem ser comuns a todos os mamíferos e que se situam nos níveis hierárquicos mais elevados, ajudando a compreender a progressão do processo puberal. Assim, todas as espécies de mamíferos estudadas, por exemplo, têm aglomerados de neurônios kisspeptinérgicos (que secretam kisspeptina), envolvidos na regulação da secreção tônica e secreção cíclica de GnRH, que também se classifica como o elemento mais alto na hierarquia desse complexo neuronal após considerar os neurônios GnRH. -/- Sabe-se que o eixo hipotálamo-hipofisário-gonodal está ativo desde as primeiras fases da vida do indivíduo, mesmo antes do nascimento em certas espécies. A secreção de GnRH, no entanto, é suprimida mais tarde no desenvolvimento e permanece dessa forma até o período pré-púbere, quando será reativada gradualmente. -/- Por várias décadas, a supressão e reinicialização dos pulsos de GnRH foi atribuída a uma hipótese conhecida como teoria gonadostat que afirma que o centro tônico do hipotálamo é inibido devido à sua sensibilidade ao mecanismo de feedback negativo dos esteroides gonodais, é aumentado; portanto, o GnRH e a consequente secreção de gonadotrofinas (FSH e LH) são insuficientes para a ocorrência da maturação folicular e espermatogênese. Essa sensibilidade diminui progressivamente à medida que a puberdade se aproxima. -/- Sabe-se agora que existem fatores não gonodais que agem em paralelo com os esteroides para mediar mudanças no feedback negativo que também são específicos da espécie. -/- Na fêmea, o centro gerador de pulso cíclico também deve ser considerado, o qual é responsável por iniciar a primeira ovulação. O centro cíclico é composto por uma segunda subpopulação de neurônios GnRH que é reativada por meio de uma complexa interação entre vários sistemas neuronais inibitórios (que devem reduzir progressiva-mente sua influência) e outros sistemas excitatórios, que, por sua vez, operam por meio de diferentes neurotransmissores, como o ácido γ-amino-butírico (GABA) e seus receptores, glutamato, óxido nítrico e neuropeptídio Y (NPY). Esses fatores, juntamente com as alterações morfológicas observadas nos neurônios do GnRH à medida que a puberdade se aproxima, e com as interações e sinais aferentes das células gliais, levam a um padrão de progressão linear que culminará na reativação do centro cíclico. Esse processo era conhecido anteriormente como teoria da maturação central e faz parte das mudanças que configuram o processo para chegar à puberdade. A elevação nas concen-trações de estradiol subsequente à reativação gradual do centro gerador de pulso tônico GnRH provavelmente permitirá a maturação final do centro cíclico. -/- A forma como cada organismo estabelece o momento certo para iniciar as mudanças que levam à puberdade é conhecido; a existência de algum mecanismo neurobiológico que constitui um relógio interno pode ser considerada. No entanto, esse mecanismo afetaria principalmente o desenvolvimento neuronal no nível central; também seria difícil compará-lo com a maneira pela qual fatores externos ao indivíduo afetam o início da puberdade. Nessa perspectiva, um sistema que permita receber informações completas sobre o crescimento e desenvolvimento do indivíduo poderia ser mais prático. Os mediadores desse sistema incluem o hormônio do crescimento, IGF-I, leptina e outros substratos metabólicos. A leptina em particular, que sinaliza as reservas de tecido adiposo, é um dos elementos mais importantes e, embora não determine quando começa a puberdade, se atua como fator permissivo para que o processo progrida, uma vez que excede um nível limite. A consideração do estágio de desenvolvimento do animal para o início da puberdade era anteriormente conhecida como o peso corporal crítico ou teoria do lipostato. É importante considerar que as três teorias mencionadas não são exclusivas. -/- O mecanismo da puberdade nos machos é semelhante ao já descrito; entretanto, deve-se lembrar que no macho o centro cíclico não está ativo. À medida que a puberdade se aproxima, o crescimento testicular é desencadeado e, em ruminantes e suínos, o pênis que estava preso à mucosa prepucial é gradualmente liberado. -/- -/- • _____FATORES QUE INFLUENCIAM A PUBERDADE -/- Os animais podem manifestar a puberdade de três formas diferentes. Pode ser tardia e o animal demorar para estar apto a reprodução; precoce e o animal entrar na vida reprodutiva antes do esperado ou pode ser normal e o animal estar com boa conformação e idade. Para tanto, alguns fatores podem interferir à manifestação da puberdade pelos animais como a genética, idade e peso, nutrição, fotoperíodo e o próprio manejo adotado. -/- -/- Genética -/- O genótipo afeta a idade da puberdade, pois algumas raças são anteriores a outras. Nos bovinos, as raças europeias atingem a puberdade antes dos zebuínos, isto é, uma novilha ou novilho da raça holandesa atinge a puberdade primeiro que os animais da mesma idade e do mesmo peso da raça nelore, por exemplo. -/- Da mesma forma, as porcas da raça chinesa Meishan atingem a puberdade por volta dos 115 dias de idade, metade da idade das raças brancas. As ovelhas de raças de corte, da mesma forma, são mais precoces que os produtores de lã. As raças pequenas, da mesma forma, são geralmente mais precoces, pelo menos em bovinos (jersey x guzerá) e em caninos. Os híbridos, por outro lado, apresentam puberdade mais precoce que os puros, devido ao efeito da heterose. Por este motivo, em certas espécies são utilizadas linhas híbridas. -/- -/- Idade e peso -/- A tabela 1 mostra a idade média de início da puberdade em espécies domésticas. O peso vivo (PV) adulto é mais relevante para a idade na puberdade nos ruminantes, enquanto em suínos é menos decisivo. A tabela também apresenta a porcentagem de peso corporal necessária para a puberdade ocorrer de forma natural. -/- -/- Tabela 1: Idade e peso a puberdade das espécies domésticas -/- Espécie -/- Fêmea (meses) -/- Macho (meses) -/- PV adulto (%) -/- Gado holandês -/- 11 (8-15) -/- 11 (7-18) -/- 30-40 -/- Gado brahman -/- 19 -/- 17 -/- 45-60 -/- Caprinos e ovinos -/- 7 (4-14) -/- 7 (6-9) -/- 40-60 -/- Suínos -/- 6 (5-7) -/- 7 (5-8) -/- 75 -/- Equinos -/- 18 (12-19) -/- 14 (10-24) -/- - -/- Caninos -/- 12 (6-24) -/- 9 (5-12) -/- - -/- Felinos -/- 8 (4-12) -/- 9 (8-10) -/- - -/- Fonte: VALENCIA, 2018. -/- Nutrição -/- Como a puberdade está relacionada à taxa de crescimento, os animais que recebem uma nutrição adequada e balanceada apresentarão puberdade em uma idade mais jovem, ou seja, mais precocemente; ao contrário, a puberdade será tardia nos animais que sofreram restrição alimentar, que estão desnutridos ou que tiveram seu crescimento afetado por doenças infecciosas ou parasitárias. A superalimentação também não é recomendada, pois pode alterar tanto os sinais que são recebidos pelo hipotálamo quanto sua resposta a eles. -/- Logo, o manejo alimentar adotado deve estar de acordo com as normas estabeleci-das pelos especialistas na área, principalmente no tocante as exigências nutricionais que devem servir de regra na propriedade. Sendo assim, os animais entrarão em puberdade com as taxas de alta qualidade o que afetará positivamente na prole futura e dará retorno lucrativo ao proprietário. -/- -/- Época do ano (Fotoperíodo) -/- Em fêmeas de espécies sazonais, como ovelhas e cabras, existem certos requisitos de fotoperíodo que devem ser atendidos para que a puberdade ocorra. Nessas espécies, um período de exposição a dias longos é necessário, seguido por outro de exposição a dias curtos. Na verdade, os cordeiros e cabritos nascidos fora da estação, mesmo que tenham atingido o peso necessário, terão que esperar até o outono seguinte (a estação reprodutiva) para atingir a puberdade. Os machos, por outro lado, não estão sujeitos a essas limitações nos requisitos fotoperiódicos para apresentar a puberdade. -/- Em novilhas nascidas no outono, por outro lado, a puberdade ocorre antes de um ano de idade, no verão seguinte ou no início do outono, mais cedo do que nas nascidas na primavera, devido à exposição a longos dias durante os primeiros seis meses do ano após seu nascimento aceleram seu crescimento. Em gatos, o aumento do fotoperíodo também acelera o início da puberdade. -/- Em ovelhas e novilhas, a primeira ovulação que ocorre ao entrar na puberdade é silenciosa; ou seja, não é acompanhada de sinais comportamentais de cio como a micção frequente, inchamento da vulva, uma montando a outra e deixando-se montar etc., pois para que esse comportamento se manifeste, o sistema nervoso necessita de uma pré-sensibilização com progesterona que não estará presente até o próximo ciclo, após o desenvolvimento do corpo lúteo vindo desta primeira ovulação. -/- -/- Sociossexual -/- A interação de indivíduos da mesma espécie ou a presença ou ausência de sinais de bioestimulação, como feromônios, pode afetar o período de puberdade. A puberdade, por exemplo, é atrasada em porcas criadas individualmente em comparação com porcas criadas em grupo. Além disso, na porca, ovelha e cabra, a exposição ao macho estimula as fêmeas e a puberdade aparece mais precocemente. -/- -/- Manejo -/- Certas práticas de manejo podem acelerar a puberdade, especialmente no período pré-púbere. Em porcas próximas à puberdade, por exemplo, o estresse causado por procedimentos, como o transporte de um local para outro ou a exposição ao macho, faz com que apareça o estro em torno de sete dias após a realização do manejo mencionado. -/- -/- • _____ESTACIONALIDADE REPRODUTIVA -/- A estacionalidade ou sazonalidade reprodutiva é uma estratégia evolutiva que se desenvolveu em algumas espécies; tende a tornar a reprodução mais eficiente. Nos países de latitudes distantes do equador, o objetivo é que as crias nasçam na primavera, época do ano mais favorável, graças à abundância de alimentos e às amenas condições climáticas. No caso da ovelha, cuja gestação dura cinco meses, para que os partos ocorram na primavera, ela deve engravidar no outono (figura 1), quando os dias são curtos; enquanto a égua, tendo uma gestação de aproximadamente 11 meses, deve conceber na primavera, quando os dias são longos; assim, o parto ocorrerá na primavera do ano seguinte (figura 2). -/- -/- Figura 1: Esquema ilustrativo da estacionalidade reprodutiva na espécie ovina. Fonte: PIRES et al., 2011. -/- -/- Esta característica evolutiva desenvolvida pela seleção natural na maioria das espécies silvestres e ainda é conservado por algumas espécies domésticas, como ovelhas, cabras, cavalos e gatos. Em bovinos e suínos, ao contrário, a domesticação levou à perda quase total da estacionalidade reprodutiva. -/- A estacionalidade reprodutiva é codificada nos genes; significa então que a seleção natural favoreceu a propagação de genes que permitiam acoplar a hora do nascimento com a melhor época do ano, por isso passou a ser considerada um método anticoncepcional natural. -/- -/- Figura 2: ciclo reprodutivo anual em espécies estacionais; onde são apresentados os períodos de gestação e a forma como se agrupam os nascimentos, independentemente da época reprodutiva da espécie, em vermelho as fêmeas estão apresentando estro ou cio. Fonte: VALENCIA, 2018. -/- -/- Fotoperíodo -/- Para sincronizar o período fértil com a época mais favorável do ano, a maioria das espécies sazonais usa o fotoperíodo (quantidade de luz diária ao longo do ano). -/- Este sinal ambiental é seguro, confiável e se repete a cada ano. Ovinos e caprinos se reproduzem na época do ano em que os dias são curtos e os equinos quando são longos. O grau de sazonalidade depende da origem da raça. As raças nativas de países localizados em latitudes elevadas (> 50°,ovelhas: soay, blackface, suffolk; cabras: saanen, alpino francês, toggenburg; equinos: puro-sangue, hanoveriano) terão uma estacionalidade mais acentuada do que as latitudes menores ou mediterrâneas (ovelhas: merino; cabras: murciana granadina; equinos: quarto de milha). Também existem raças de latitudes próximas ao Equador cuja estacionalidade é baixa ou nula (ovelhas: raças de pelo, crioulas; cabras: raças africanas e asiáticas) (tabela 2). -/- Para a maioria das raças de ovinos e caprinos, a estação reprodutiva começa no final do verão e início do outono; caracteriza-se pela apresentação de ciclos estrais sucessivos, e termina no final do inverno, quando se inicia o anestro, que se caracteriza pela ausência de ovulação. Nos equinos, ocorre o contrário, uma vez que a estação reprodutiva ocorre na primavera e no verão. -/- -/- Tabela 2: Relação entre a origem da raça e o grau de estacionalidade ou sazonalidade -/- Espécie -/- Alta -/- Média -/- Baixa -/- Ovinos -/- Suffolk, raças britânicas de lã e corte -/- Merino -/- Pelibuey, crioulas -/- Caprinos -/- Saanen, alpino, toggenburg -/- Murciana granadina -/- Crioula -/- Equinos -/- Puro-sangue, hanoveriano, quarto de milha -/- - -/- Crioula, burros -/- Fonte: VALENCIA, 2018. -/- -/- Mecanismo neuroendócrino da estacionalidade -/- Durante o período de anestro, o fotoperíodo exerce efeito inibitório sobre o centro tônico do GnRH no hipotálamo, diminuindo a frequência de pulso. Consequentemente, a pulsatilidade do LH também diminui, que agora é incapaz de induzir a maturação folicular, o aumento dos estrogênios, o pico pré-ovulatório de LH e, portanto, a ovulação. -/- Isso ocorre porque durante o anestro a sensibilidade do hipotálamo ao mecanismo de feedback negativo dos estrogênios e de outros fatores de origem não gonodal é aumentada. Ao aproximar-se da estação reprodutiva, a sensibilidade hipotalâmica diminui e o aumento da pulsatilidade do GnRH causa as mudanças que culminam na ovulação. Portanto, o mecanismo endócrino do anestro estacional é semelhante ao do anestro pré-púbere e de alguns outros tipos de anestro. -/- A estacionalidade é um bom exemplo da interação entre o meio ambiente e o sistema neuroendócrino, pois o organismo é capaz de traduzir um sinal externo ambiental, como o fotoperíodo, em um sinal hormonal interno, que neste caso é a melatonina. -/- A glândula pineal secreta melatonina durante as horas de escuridão. Os animais sazonais apresentam um ritmo reprodutivo endógeno, que é regulado por janelas de fotossensibilidade, determinadas por mudanças na duração do dia. O sinal luminoso é captado pela retina e conduzido, via nervo, pelo trato retino-hipotalâmico até o núcleo supraquiasmático, que funciona como o relógio biológico do corpo. Daí o sinal viaja para o núcleo para-ventricular, depois para o gânglio cervical e, finalmente, para a glândula pineal, que responde secretando melatonina (figura 3). -/- Nas ovelhas, a estação reprodutiva começa quando a duração do dia diminui e, naturalmente, a noite aumenta; na égua, ocorre quando os dias se alongam. -/- A primavera não é necessariamente a melhor época do ano em todas as regiões do globo. Nas latitudes tropicais, a primavera coincide com a seca e não com a abundância de forragem, aspecto a ser levado em consideração ao programar a reprodução. -/- Outro ponto importante a considerar é que as raças europeias sazonais mantêm sua estacionalidade no Brasil. -/- -/- Figura 3: Mecanismo do fotoperíodo em ovinos e a melatonina. Fonte: HAFEZ, 2004. -/- -/- Estacionalidade no macho -/- O macho é menos afetado que a fêmea pelas mudanças típicas de cada época do ano, já que sua função reprodutiva não é necessariamente interrompida durante o anestro ou repouso sexual, embora a produção de hormônios reprodutivos, tamanho e tônus testicular, a libido, as características qualitativas e quantitativas do ejaculado e a fertilidade do esperma podem ser diminuídas. O nível de afetação depende do grau de sazonalidade da raça e da latitude. Por fim, os efeitos do fotoperíodo devem ser separados dos nutricionais, que também variam com a época do ano. -/- -/- REFERÊNCIAS BIBLIOGRÁFICAS -/- -/- BEARDEN, Henry Joe et al. Reproducción animal aplicada. México: Manual Moderno, 1982. -/- BROOKS, P. H.; COLE, D. J. A. The effect of the presence of a boar on the attainment of puberty in gilts. Reproduction, v. 23, n. 3, p. 435-440, 1970. -/- CARDOSO, Daniel; DE PAULA NOGUEIRA, Guilherme. Mecanismos neuroendócrinos envolvidos na puberdade de novilhas. Arquivos de Ciências Veterinárias e Zoologia da Unipar, v. 10, n. 1, 2007. -/- CHEMINEAU, P. et al. Induction and persistence of pituitary and ovarian activity in the out-of-season lactating dairy goat after a treatment combining a skeleton photoperiod, melatonin and the male effect. Reproduction, v. 78, n. 2, p. 497-504, 1986. -/- CLARKE, Iain J. et al. Kisspeptin and seasonality in sheep. Peptides, v. 30, n. 1, p. 154-163, 2009. -/- CORTEEL, J. M. Production, storage and insemination of goat semen. In: Management and Reproduction in Sheep and Goats Symposium, Madison, Wis. (USA), 1977. University of Wisconsin, 1977. -/- CUNNINGHAM, James. Tratado de fisiologia veterinária. Elsevier Health Sciences, 2011. -/- CUPPS, Perry T. (Ed.). Reproduction in domestic animals. Elsevier, 1991. -/- DUKES, Henry Hugh; SWENSON, Melvin J.; REECE, William O. Dukes fisiologia dos animais domésticos. Editora Guanabara Koogan, 1996. -/- DÝRMUNDSSON, Ó. R.; LEES, J. L. Effect of rams on the onset of breeding activity in Clun Forest ewe lambs. The Journal of Agricultural Science, v. 79, n. 2, p. 269-271, 1972. -/- EBLING, F. J. P.; FOSTER, D. L. Photoperiod requirements for puberty differ from those for the onset of the adult breeding season in female sheep. Reproduction, v. 84, n. 1, p. 283-293, 1988. -/- FIELDS, Michael J.; SAND, Robert S.; YELICH, Joel V. (Ed.). Factors affecting calf crop: Biotechnology of reproduction. CRC Press, 2001. -/- HAFEZ, Elsayed Saad Eldin; HAFEZ, Bahaa. Reprodução animal. São Paulo: Manole, 2004. -/- HUGHES, P. E.; PHILIP, G.; SISWADI, R. The effects of contact frequency and transport on the efficacy of the boar effect. Animal Reproduction Science, v. 46, n. 1-2, p. 159-165, 1997. -/- KARSCH, FRED J. et al. Neuroendocrine basis of seasonal reproduction. In: Proceedings of the 1983 Laurentian Hormone Conference. Academic Press, 1984. p. 185-232. -/- LINCOLN, G. A.; SHORT, R. V. Seasonal breeding: nature's contraceptive. In: Proceedings of the 1979 Laurentian Hormone Conference. Academic Press, 1980. p. 1-52. -/- MELLO, Raquel Rodrigues Costa. Puberdade e maturidade sexual em touros bovinos. Agropecuária Científica no Semiárido, v. 10, n. 3, p. 11-28, 2015. -/- MEZA‐HERRERA, C. A. et al. Neuroendocrine, metabolic and genomic cues signalling the onset of puberty in females. Reproduction in Domestic Animals, v. 45, n. 6, p. e495-e502, 2010. -/- MONTEIRO, Claudia Dias; BICUDO, Sony Dimas; TOMA, Hugo Shisei. Puberdade em fêmeas ovinas. Pubvet, v. 4, p. Art. 850-857, 2010. -/- OLIVEIRA, Daniel de Jesus Cardoso de. Mecanismos neuroendócrinos envolvidos na puberdade de novilhas da raça Nelore. 2006. Tese de Doutorado em Medicina Veterinária. Universidade de São Paulo. -/- OLSTER, DEBORAH H.; FOSTER, DOUGLAS L. Control of gonadotropin secretion in the male during puberty: a decrease in response to steroid inhibitory feedback in the absence of an increase in steroid-independent drive in the sheep. Endocrinology, v. 118, n. 6, p. 2225-2234, 1986. -/- PIRES, Bruno Carlos et al. Métodos para elevar o ritmo reprodutivo dos ovinos. PUBVET, Londrina, V. 5, N. 11, Ed. 158, Art. 1071, 2011. -/- PLANT, Tony M.; ZELEZNIK, Anthony J. (Ed.). Knobil and Neill's physiology of reproduction. New York: Academic Press, 2014. -/- RAMIREZ, Domingo V.; MCCANN, S. M. Comparison of the regulation of luteinizing hormone (LH) secretion in immature and adult rats. Endocrinology, v. 72, n. 3, p. 452-464, 1963. -/- ROSER, JANET F.; HUGHES, JOHN P. Seasonal effects on seminal quality, plasma hormone concentrations, and GnRH‐induced LH response in fertile and subfertile stallions. Journal of andrology, v. 13, n. 3, p. 214-223, 1992. -/- SALOMONI, Eduardo et al. Idade e peso à puberdade em fêmeas de corte puras e cruzas em campo natural. Pesquisa Agropecuária Brasileira, v. 23, n. 10, p. 1171-1179, 1988. -/- SMITH, Jeremy T.; CLARKE, Iain J. Seasonal breeding as a neuroendocrine model for puberty in sheep. Molecular and cellular endocrinology, v. 324, n. 1-2, p. 102-109, 2010. -/- VALENCIA, J. Pubertad y estacionalidad reproductiva. In. PORTA, L. R.; MEDRANO, J. H. H. Fisiología reproductiva de los animales domésticos. Cidade do México: FMVZ-UNAM, 2018. -/- WHITTEMORE, Colin et al. The science and practice of pig production. Blackwell Science Ltd, 1998. -/- -/- -/- FIXAÇÃO DO ASSUNTO -/- -/- 1. Defina o que é puberdade e como ela manifesta-se no corpo. -/- -/- -/- 2. Diferencie puberdade de maturidade sexual. -/- -/- -/- 3. Quais são os fenômenos que devem ser observados em fêmeas que estão entrando na puberdade? -/- -/- -/- 4. Qual o papel do GnRH e do IGF-I sobre a puberdade? -/- 5. Um produtor possui duas ovelhas e um carneiro reprodutor, as ovelhas possuem idade e peso, mas não manifestaram seu primeiro cio, quais elementos que você recomenda ao produtor para induzir a ciclicidade dessas fêmeas? -/- -/- -/- 6. De forma geral, quais os fatores que podem afetar a entrada na puberdade dos animais? -/- -/- -/- 7. Defina estacionalidade reprodutiva. -/- -/- -/- 8. O que é fotoperíodo e qual sua importância para a reprodução dos animais domésticos? -/- -/- -/- 9. Defina as relações existentes entre a origem da raça e o grau de estacionalidade e como tais teorias se aplicam ao rebanho brasileiro. -/- -/- -/- 10. Qual o papel da glândula pineal para a estacionalidade reprodutiva? -/- -/- -/- 11. Por que os machos são menos afetados pela sazonalidade reprodutiva do que as fêmeas? -/- -/- -/- 12. Sabendo-se sobre os termos de puberdade e estacionalidade e as características de ambos nas espécies domésticas, pede-se: um criador deseja obter 5 novas crias ovinas e 5 caprinas em seu plantel até o final do ano, para tanto ele ainda possui um ano e está na estação do verão, sabendo-se sobre a estacionalidade dessas espécies elabore um projeto reprodutivo de modo que essas 10 fêmeas possam gerar uma cria cada até a primavera. -/- -/- Dados: 10 fêmeas gerando 10 crias. 1 macho ovino e 1 caprino. Fêmeas com 1 ano de idade (2º cio) e peso corporal = 55% do peso adulto. Verão de 2020 para parir na primavera de 2020. (shrink)

Aggregating individuals’ consistent attitudes might produce inconsistent collective attitudes. Some groups therefore need the capacity to form attitudes that are irreducible to those of their members. Such groups, group-agent realists argue, are agents in control of their own attitude formation. In this paper, however, I show how group-agent realism overlooks the important fact that groups consist of strategically interacting agents. Only by eliminating group agency from our social explanations can we see how individuals vote strategically to gain control of their (...) groups and produce collective attitudes we cannot make sense of if we treat groups as agents. (shrink)

In this article, I discuss and demonstrate how research into real‐world scientific problem‐solving provides a novel window on the mind and insight into the human capacity to design and utilize resource rich environments at the highly creative end of the cognitive spectrum.

While philosophical questions about health and disease have attracted much attention in recent decades, and while opinions are divided on most issues, influential accounts seem to embrace negativism about health, according to which health is the absence of disease. Some subscribe to unrestricted negativism, which claims that negativism applies not only to the concepts of health and disease as used by healthcare professionals but also to the lay concept that underpins everyday thinking. Whether people conceptualize health in this manner has (...) implications for medical care and public health, and so we set out to examine this claim in two studies. Participants were asked to assess and compare the health states of two people presented in two vignettes. We found that both lay people and medical students conceptualize health as something more than the absence of disease. We argue that our findings highlight a need to rethink unrestricted negativism and indicate a need to rethink the way the debate has traditionally focused on disease. (shrink)

In their Why Machines Will Never Rule the World, Landgrebe and Smith (2023) argue that it is impossible for artificial general intelligence (AGI) to succeed, on the grounds that it is impossible to perfectly model or emulate the “complex” “human neurocognitive system”. However, they do not show that it is logically impossible; they only show that it is practically impossible using current mathematical techniques. Nor do they prove that there could not be any other kinds of theories than those in (...) current use. Even if perfect theories were impossible or unlikely, perfection may not be needed and may even be unhelpful. (shrink)

How can work be a genuine good in life? I argue that this requires overcoming a problem akin to that studied by Marx scholars as the problem of work, freedom and necessity: how can work be something we genuinely want to do, given that its content is not up to us, but is determined by necessity? I argue that the answer involves valuing contributing to the good of others, typically as valuing active pro-sociality – that is, valuing actively doing something (...) good for others. This makes work better in one way, and may even make work something we are genuinely glad to have in our lives. Contemporary philosophical thinking about good work tends to focus on how work can be good for the person doing it, by providing, for example, self-realization or social relationships, while underappreciating the special importance of valuing social contribution. People will typically only really want work if they want a part of their lives to be about the good of others. This also means that work may be a part of the best life, something we should take into account when discussing work-related policies and the desirability of a ‘post-work’ future. (shrink)

Every account of moral responsibility has conditions that distinguish between the consequences, actions, or traits that warrant praise or blame and those that do not. One intuitive condition is that praiseworthiness and blameworthiness cannot be affected by luck, that is, by factors beyond the agent’s control. Several philosophers build their accounts of moral responsibility on this luck-free condition, and we may call their views Luck-Free Moral Responsibility (LFMR). I offer moral and metaphysical arguments against LFMR. First, I maintain that considerations (...) of fairness that often motivate LFMR do not require its adoption. Second, I contend that LFMR has counterintuitive implications for the nature and scope of praiseworthiness and blameworthiness and that LFMR is vulnerable to a reductio ad absurdum. Third, I state some common reasons for thinking that LFMR’s commitment to true counterfactuals of libertarian freedom is problematic, and I argue that if there are no such true counterfactuals and if LFMR is true, a person is praiseworthy and blameworthy at most for a tiny fraction of her actions. Fourth, I argue that proponents of LFMR cannot escape this skeptical cost by appealing to a different kind of counterfactual of freedom. Fifth, I develop an anti-skeptical motivation to affirm the idea that luck can affect moral responsibility. (shrink)

In the topic-sensitive theory of the logic of imagination due to Berto (2018a), the topic of the imaginative output must be contained within the imaginative input. That is, imaginative episodes can never expand what they are about. We argue, with Badura (2021), that this constraint is implausible from a psychological point of view, and it wrongly predicts the falsehood of true reports of imagination. Thus the constraint should be relaxed; but how? A number of direct approaches to relaxing the controversial (...) content-inclusion constraint are explored in this paper. The core idea is to consider adding an expansion operator to the mereology of topics. The logic that results depends on the formal constraints placed on topic expansion, the choice of which are subject to philosophical dispute. The rst semantics we explore is a topological approach using a closure operator, and we show that the resulting logic is the same as Berto's own system. The second approach uses an inclusive and monotone increasing operator, and we give a sound and complete axiomatisation for its logic. The third approach uses an inclusive and additive operator, and we show that the associated logic is strictly weaker than the previous two systems, and additivity is not de nable in the language. The latter result suggests that involved techniques or a more expressive language is required for a complete axiomatization of the system, which is left as an open question. All three systems are simple tweaks on Berto's system in that the language remains propositional, and the underlying theory of topics is unchanged. (shrink)

A modern and influential Aristotelian conception of universals combines two ideas: that a universal is immanent in its instantiations, and that its instantiations are partly constructed by this universal. I argue that these two ideas are inconsistent on weaker assumptions than previously recognized.

Does the evidence that our universe contains fine-tuned life confirm the multiverse hypothesis? The answer depends on our approach to self-locating beliefs. In a recent paper, Isaacs, Hawthorne, and Russell (2022) offer two arguments for thinking that such evidence does confirm the multiverse hypothesis. First, they argue that the three leading approaches to self-locating beliefs all entail that such evidence confirms the multiverse hypothesis. Second, they present a pair of theorems showing that any approach to self-locating beliefs that satisfies certain (...) “reasonable” constraints will entail that such evidence confirms the multiverse hypothesis. I argue that Isaacs, Hawthorne, and Russell’s two arguments are not compelling, the first because they fail to consider some natural approaches to self-locating beliefs, the second because their theorems rely on a suspect premise that we should reject. Contra Issacs, Hawthorne, and Russell, I argue that on a natural approach to self-locating beliefs the evidence that our universe contains fine-tuned life needn’t confirm the multiverse hypothesis. (shrink)

Ernest Sosa (1940-) is a central figure in contemporary epistemology. He is best known for pioneering the subfield of virtue epistemology, as well as developing across four decades his own distinctive framework in this tradition. Besides providing an overview of this work, this article offers a guide to Sosa’s other contributions to epistemology, stretching back to his first publication in 1964. The organization is as follows. §1 reviews Sosa’s distinctive brand of virtue epistemology and its development since 1980. §2 provides (...) a fuller synopsis of Sosa’s contributions to epistemology in five parts, covering his work on (i) the structure of justification and knowledge, (ii) the dawning of knowledge and understanding, (iii) skepticism and the possibility of empirical knowledge, (iv) methodology and the possibility of philosophy, and (v) the relationship between mind and world. Our aim is to encourage renewed appreciation of the full scope and depth of Sosa’s epistemology. We hope the reader will benefit from (re)exploring Sosa’s work guided by the map detailed below. (shrink)

Recently, a version of realism has been offered to address the simplification strategies used in computational neuroscience (Chirimuuta, 2023; 2024). According to this view, computational models provide us with knowledge about the brain, but they should not be taken literally in any sense, even rejecting the idea that the brain performs computations (computationalism). I acknowledge the need for considerations regarding simplification strategies in neuroscience and how they contribute to our interpretations of computational models; however, I argue that whether we should (...) accept or reject computationalism about the brain is a separate issue that can be addressed independently by a philosophical theory of physical computation. This takes seriously the idea that the brain performs computations while also taking an analogical stance toward computational models in neuroscience. I call this version of realism “Analogical Computational Realism.” Analogical Computational Realism is a realist view in virtue of being committed to computationalism while taking certain computational models to pick out real patterns (Dennett, 1991; Potochnik, 2017) that provide a how-possibly explanation without also thinking that the model is literally implemented in the brain. (shrink)

The article presents a pluralistic model of value change, emphasizing the interplay between technology and societal values. It critiques the Simple Change Model, which suggests a uniform transition from one dominant value scheme to another, arguing instead for emergent and differential value change. Emergent value change occurs when new values arise within specific contexts without displacing existing ones, often influenced by generational experiences with technology and niches where new technologies are introduced. Differential value change highlights how distinct groups may adopt (...) different value schemes based on their unique contexts and experiences, sometimes leading to societal polarization and the need to reconcile incompatible value schemes. The article stresses the importance of individual experiences of ethical uncertainty and disruption in understanding these changes. By integrating these complexities, the model offers a rich, non-deterministic framework for analyzing how values evolve in response to technological advancements. (shrink)

Philosophers and social scientists largely agree that fake news is not just necessarily untruthful, but necessarily insincere: it’s produced either with the intention to deceive or an indifference toward its truth. Against this, I argue insincerity is neither a necessary nor obviously typical feature of fake news. The main argument proceeds in two stages. The first, methodological step develops classification criteria for identifying instances of fake news. By attending to expressed theoretical and practical interests, I observe how our classification practices (...) turn on worries about fake news’s unique political-epistemic risks. From this, I argue (i) theories of fake news should capture independent mechanisms that realise these risks and (ii) the manifestation of them suffices for classifying a news story as fake news. The second step applies the classification criteria to bad science journalism. I argue the systematic epistemic faults in bad science journalism manifest the same political-epistemic risks we see in fake news, which suffices to justify classifying it as fake news. But since such faults aren’t plausibly attributed to its propagators being insincere, insincerity doesn’t function independently as a mechanism for realising fake news’s political-epistemic risks. Thus, I conclude, we should exclude insincerity from our accounts of the phenomenon. (shrink)

Perception is a central means by which we come to represent and be aware of particulars in the world. I argue that an adequate account of perception must distinguish between what one perceives and what one's perceptual experience is of or about. Through capacities for visual completion, one can be visually aware of particular parts of a scene that one nevertheless does not see. Seeing corresponds to a basic, but not exhaustive, way in which one can be visually aware of (...) an item. I discuss how the relation between seeing and visual awareness should be explicated within a representational account of the mind. Visual awareness of an item involves a primitive kind of reference: one is visually aware of an item when one's visual perceptual state succeeds in referring to that particular item and functions to represent it accurately. Seeing, by contrast, requires more than successful visual reference. Seeing depends additionally on meta-semantic facts about how visual reference happens to be fixed. The notions of seeing and of visual reference are both indispensable to an account of perception, but they are to be characterized at different levels of representational explanation. (shrink)

One proposed explanation for a particular kind of temporal preference lies in a disparity between the emotional intensity of memory compared to anticipation. According to the memory/anticipation disparity explanation, the utility of anticipation of a particular event if that event is future, whether positive or negative, is greater than the utility of retrospection of that same event if it is past, whether positive or negative, and consequently, overall utility is maximised when we prefer negative events to be located in the (...) past rather than the future, and positive ones in the future rather than the past. To have this preference is to be (at least apparently) future biased. If this explanation is correct, it would tend to confer rational justification upon these preferences. This paper empirically investigates this explanation. Our results suggest that, at most, this explanation might be a partial one of some people’s preferences some of the time, rather than a general explanation of future bias. In turn, this lends some indirect support to a competing explanation that appeals to temporal asymmetries in emotion and attention. Since that explanation would arguably tend not to confer rational justification upon (apparently) future-biased preferences, we argue that our findings provide some reason to be sceptical that these preferences are, in general, rationally justified. (shrink)

Naive realism in philosophy of perception is the view that (successful) perception involves a direct relation between perceiving subjects and the world. The naive realist says that your perception of a cat on the mat is a worldly relation which is partially constituted by the cat and the mat; a spatio-temporal chunk of the world is presenting itself to you. Recently, Elijah Chudnoff and John Bengson have independently developed an extension of this view to intellectual experiences, or intuitions, for traditionally (...) a priori domains. We argue that this view, which we call ‘Intuitional Naive Realism’ (INR), will not have the epistemic advantages that Chudnoff and Bengson claim that it does. In perception, but not intuition, there is a deeper explanation of what makes it the case that one experience is constituted by the world while another is not. Whether or not INR is true, then, it does no interesting epistemological work for traditionally a priori domains. (shrink)

Perception involves the processing of content or information about the world. In what form is this content represented? I argue that perception is widely compositional. The perceptual system represents many stimulus features (including shape, orientation, and motion) in terms of combinations of other features (such as shape parts, slant and tilt, common and residual motion vectors). But compositionality can take a variety of forms. The ways in which perceptual representations compose are markedly different from the ways in which sentences or (...) thoughts are thought to be composed. I suggest that the thesis that perception is compositional is not itself a concrete hypothesis with specific predictions; rather it affords a productive framework for developing and evaluating specific empirical hypotheses about the form and content of perceptual representations. The question is not just whether perception is compositional, but how. Answering this latter question can provide fundamental insights into perception. (shrink)

While many aspects of cognition have been shown to be shared between humans and non-human animals, there remains controversy regarding whether the capacity to mentally time travel is a uniquely human one. In this paper, we argue that there are four ways of representing when some event happened: four kinds of temporal representation. Distinguishing these four kinds of temporal representation has five benefits. First, it puts us in a position to determine the particular benefits these distinct temporal representations afford an (...) organism. Second, it provides the conceptual resources to foster a discussion about which of these representations is necessary for an organism to count as having the capacity to mentally time travel. Third, it enables us to distinguish stricter from more liberal views of mental time travel that differ regarding which kind(s) of temporal representation is taken to be necessary for mental time travel. Fourth, it allows us to determine the benefits of taking a stricter or more liberal view of mental time travel. Finally, it ensures that disagreement about whether some species can mentally time travel is not merely the product of unrecognised disagreement about which temporal representation is necessary for mental time travel. We argue for a more liberal view, on the grounds that it allows us to view mental time travel as an evolutionarily continuous phenomenon, and to recognise that differences in the ways that organisms mentally time travel might reflect different temporal representations, or combinations thereof, that they employ. Our ultimate aim, however, is to create the conceptual framework for further discussion regarding what sorts of temporal representations are required for mental time travel. (shrink)

The physicalist credo is that the world is physical. But some phenomena, such as minds, morals, and mathematics, appear to be nonphysical. While an uncompromising physicalism would reject these, a conciliatory physicalism needn’t if it can account for them in terms of an underlying physical basis. Any such account must refer to the nonphysical. But won’t this unavoidable reference to the nonphysical conflict with the physicalist credo? This essay aims to clarify this problem and introduce a novel solution that relies (...) on a distinction between “circumstantial” facts that are based in the circumstances and “acircumstantial” facts that are not. This is used in two ways. First, physicalism is restricted to circumstantial facts: only they must have a physical basis that does not refer to the nonphysical. Second, facts accounting for the nonphysical are not restricted to the circumstantial: they may refer to the nonphysical if they are acircumstantial. Facts about how the physical accounts for the nonphysical therefore do not conflict with the physicalist’s credo. This provides a credible answer to what physicalism could be. (shrink)

Prior research has unveiled a pathologization effect where individuals perceived as having bad moral character are more likely to have their conditions labeled as diseases and are less often considered healthy compared to those viewed as having a good moral character. Moreover, these individuals are perceived as less unlucky in their affliction and more deserving of it. This study explores the broader impacts of moral character on such judgments, hypothesizing that these effects reach deeper and extend to both negative and (...) positive moral evaluations. The pathologization effect also raises concerns about potential discrimination and the overmedicalization of normal health variations, so we also examine whether providing more detailed descriptions of conditions mitigates the influence of judgments of moral character. The methodology and broader implications of our findings are discussed, emphasizing the need for a deeper understanding of how moral judgments might influence patient care. (shrink)

This chapter will discuss the relation of physicalism to social ontology, and explores problems that social ontology raises for physicalism. Physicalism is often understood to be the view that all facts—the social ones included—are physical facts, or at least are exhaustively determined by physical facts. While this view is widely endorsed, social phenomena challenge physicalism in several ways, both challenging the coherence of claims of physicalism and raising potential counterexamples.

This article aims to shed light on the possible influence of the Kabbalah on Spinoza. To do this, I will analyze the role that the Kabbalist theoretical model may have had on the development of Spinozist philosophy, in order to understand both their convergences and their divergences. I will then clarify Spinoza's relationship to this theory, especially the Lurianic Kabbalah, and emphasize the importance of the notion of Tsimtsum (contraction of the Divine light).

Objectives Practitioners in contemplative traditions commonly report experiencing an awareness that is distinct from sensory objects, thoughts, and emotions (“awareness itself”). They also report experiences of a void or underlying silence that is closely associated with this awareness. Subjects who carry out the Headless Way exercises frequently report an experience of emptiness or void at the same time as other contents (void-like experiences). The goals of this study were to (1) assess the reliability of these methods in eliciting the recognition (...) of awareness and void-like experiences in participants who had no prior exposure to these techniques, (2) investigate the prevalence of these experiences in these tasks, and (3) to differentiate these experiences from closely related and potential precursor experiences. -/- Method Twenty adults participated in in-depth individual interviews in which they were guided through the Headless Way exercises. A thematic analysis was conducted on the interview transcripts. -/- Results Twelve of the participants reported a void-like experience, and five participants reported an experience of awareness itself. These experiences were respectively categorized as subsets of the more general categories of perceptual absences and the sense of not being person-like. Another novel finding was the real-time reports of awareness and void-like experiences during the exercises. -/- Conclusions Our findings provide preliminary evidence that the Headless Way exercises can effectively induce experiences of emptiness and awareness in participants without prior experience. The findings suggest that such experiences can be elicited outside of a traditional meditation context, including in non-meditators. Furthermore, the experience of not being person-like and of perceptual absences may be precursors and more general forms of recognizing awareness itself and the void-like nature of the mind. (shrink)

In this article, I argue that Kant’s Categorical Imperative applies to maxim tokens rather than to maxim types. The article has three main parts. In the first, I explain my thesis. In the second, I argue for it. In the third, I argue, further, that, if my thesis is correct, then tokens of different maxim types can have different deontic statuses for different agents.

Automated influence is one of the most pervasive applications of artificial intelligence in our day-to-day lives, yet a thoroughgoing account of its associated individual and societal harms is lacking. By far the most widespread, compelling, and intuitive account of the harms associated with automated influence follows what I call the control argument. This argument suggests that users are persuaded, manipulated, and influenced by automated influence in a way that they have little or no control over. Based on evidence about the (...) effectiveness of targeted advertising as well as empirical results about the nature of attentional control, I provide reasons to reject this argument. In turn, I use C. Thi Nguyen’s theory of value collapse to develop a new account of the harmfulness of automated influence. (shrink)

A collection of original and innovative essays that compare the justice issues raised by climate engineering to the justice issues raised by competing approaches to solving the climate problem.

Biodiversity loss is an immense ecological crisis of our time. But while “biodiversity” has become a buzzword in media and policy, conservationists have found it difficult to build a common understanding on the nature and severity of biodiversity loss and the means to tackle it. Perhaps surprisingly, many biologists and philosophers have proposed that biodiversity might be best defended with reference to its aesthetic value. This article explores whether aesthetic values could provide strong support for biodiversity conservation. By exploring the (...) question from the viewpoints of species diversity, ecosystem diversity, and genetic diversity, we argue that there is a mismatch between apparent and real biodiversity and that aesthetics can, at best, give only limited support for biodiversity conservation. (shrink)

Automated influence is one of the most pervasive applications of artificial intelligence in our day-to-day lives, yet a thoroughgoing account of its associated individual and societal harms is lacking. By far the most widespread, compelling, and intuitive account of the harms associated with automated influence follows what I call the control argument. This argument suggests that users are persuaded, manipulated, and influenced by automated influence in a way that they have little or no control over. Based on evidence about the (...) effectiveness of targeted advertising as well as empirical results about the nature of attentional control, I provide reasons to reject this argument. In turn, I use C. Thi Nguyen's theory of value collapse to develop a new account of the harmfulness of automated influence. (shrink)

In this article, I confront Jessica Flanigan’s recent attempt to show not merely that women have a right to commit prenatal injury, but also that women who act on this right are praiseworthy and should not be criticized for this injury. I show that Flanigan’s arguments do not work, and I establish presumptive grounds against any such right—namely, prenatal injury, by definition, involves intentional or negligent harm and, as such, may be subsumed under a wider class of actions that are (...) presumptively wrong. (shrink)

La question des rapports du spinozisme à l’axiologie a fait l’objet de nombreux débats. Certains commentateurs considèrent Spinoza comme étant profondément immoraliste, alors que pour d’autres, il maintient l'ensemble des valeurs humaines. Spinoza a cherché à dépasser l’utilitarisme propre au conatus de chacun, afin de fonder un altruisme rationnel. Il souligne que le bien auquel l’homme aspire lorsqu’il suit la vertu, il le désirera aussi pour tous les autres hommes. Cependant, les moyens mis en œuvre pour démontrer cette thèse semblent (...) problématiques. Cet article analyse la logique de la coopération interhumaine élaborée par Spinoza, ainsi que son idéal de l’homme libre, montrant, qu'en fait, il n'a pas réussi à surmonter la nature profondément égoïste du conatus. -/- The question of the relationship between Spinozism and axiology has been the subject of much debate. Some commentators consider Spinoza to be profoundly immoralist, while for others he upholds the set of human values. Spinoza sought to go beyond the utilitarianism proper to the conatus of each person, in order to establish a rational altruism. He emphasizes that the good to which man aspires when he follows virtue, he will also desire for all other men. However, the means used to demonstrate this thesis seem problematic. This article analyzes Spinoza's logic of interhuman cooperation, as well as his ideal of the free man, showing that, in fact, he failed to overcome the profoundly egoistic nature of conatus. -/- . (shrink)

It is now widely expected that climate change will be serious enough that a very large number of people will be displaced from their homes because of events relating to or resulting from climate change. Such events may include rising sea levels (and resulting increased salination of ground water), stronger hurricanes and tropical storms, drought, floods, increased and more intense wildfires, and other extreme or (previously) unusual weather events. Although estimates vary widely, it seems very likely that many millions of (...) people—perhaps hundreds of millions if sufficient precautions are not taken—will be forced from their homes by these events related to climate change. In the public imagination, much of the attention has been on ‘climate refugees’, where this is taken to mean people who have crossed borders. However, there is good reason to believe that a very large percentage—probably a significant majority—of displacement resulting from climate change will be, or could be, internal. In this chapter I argue that there are likely to be a large number of cases where internal displacement related to climate change is of international concern, and where, therefore, states have significant moral reasons to provide assistance, either directly to those displaced, or else to the state in which the displacement has taken place. My claim is that internal displacement arising from climate change is of international concern and so grounds a duty of aid by states able to provide it, when this displacement threatens the basic human rights of those displaced, and when the local or domestic government cannot or will not take the necessary steps to meet the needs and protect the rights of those who are displaced. (The uploaded version of this paper is an uncorrected proof. Please cite and refer to the published version.). (shrink)

Edward Stuart Russell (1887–1954) was a central figure in the philosophy of biology during the first half of the twentieth century. Although he worked as a government fisheries scientist for much of his life, he still managed to establish himself as one of the most prominent biological theorists of his time. The views he developed, which were antireductionistic, organism-centred, and teleological, challenged the prevailing mechanistic orthodoxy. His book 'The Interpretation of Development and Heredity' (1930) provides one of themost incisive critiques (...) of the chromosomal theory of the gene ever published, and it has acquired a renewed relevance in light of recent empirical findings. Russell’s interest in the theoretical problems of biology is as much historical as philosophical, and many of his works, particularly his first book 'Form and Function' (1916), are still regarded today as landmark contributions to the history of biological thought. (shrink)

In light of rampant fake news and disinformation in today's press and social media, I provide a new consequentialist argument that regulations on the media pertaining to certain false verifiable empirical facts are warranted. This contention is based in part on a collection of pre-existing empirical findings that I newly piece together from political science and psychology demonstrating that a post-truth society is likely with current media. My position is then defended from several counters, such as that it violates deontological (...) rights to free speech and to freedom of the press, that free speech leads to the acquisition of truth, and that government regulators can be biased and corrupt. (shrink)